Generic Avapro (Irbesartan)
Avapro
Avapro is used to treat hypertension and kidney problems (diabetic nephropathy) caused by diabetes.
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Product Description

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Common use

Antihypertensive drug, antagonist of angiotensin receptors II. It specifically and irreversibly blocks receptors of angiotensin which leads to diminishing of biological effects of angiotensin II. Angiotensin II effects include vasoconstriction and stimulating influence on excretion of aldosterone and activation of sympathetic nervous system. As a consequence arterial pressure diminishes and the heart does not have to work as hard to pump blood. It does not influence concentration or triglycerides, content of cholesterol, glucose, uric acid in blood plasma and excretion of uric acid with urine.



Dosage and direction

Initial dose is 150 mg and it can be increased up to 300 mg on necessity. In some cases as low chloride diet, treatment with certain diuretics and others initial dose size should be smaller. Avapro is taken once a day preferably at the same time.



Precautions

It should be administered with kidney or liver failure, congestive heart failure, after strong vomit or diarrhea and also during simultaneous treatment with potassium saving diuretics or medications containing potassium. This drug causes serious harm to unborn baby (possibly death) if it is administered and used during the last six months of pregnancy.



Contraindications

Pregnancy, infancy, hypersensitivity to Avapro.



Possible side effect

The most common side effects include diarrhea, abdominal pain or heartburn. In case you experience allergic reaction to the medication (fever, difficult breathing, hives) contact your doctor. Avapro can cause a condition that results in the breakdown of skeletal muscle tissue and then in kidney failure. Also call your doctor if you have muscle pain, tenderness, or weakness especially if you also have vomiting, and dark colored urine, difficult urination.



Drug interaction

No important drug interactions were described for this medication. At simultaneous intake with potassium-saving diuretics level of potassium may increased in blood plasma.



Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.



Overdose

Immediate medical help is needed in case of overdose which symptoms include fast or slow heartbeat, dizziness.



Storage

Tablets should be stored at room temperature, 15-30 C (59-86 F).



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Women's Health

Talking about women's health we usually mean a number of issues that are associated with women's physiology and anatomy. These issues usually includes gynecological diseases, pregnancy and breastfeeding, menopause, contraception and diseases that are peculiar only to women sex.

Gynecological diseases usually includes infectious diseases that are transmitted through the sexual intercourse. These may be viral, bacterial or fungal infection. The gynecological infections usually manifest in the form of inflammation, edema, redness, itching, discharges, pain in the pelvic area.

Menstruation, pregnancy and breastfeeding are related to the women's reproductive system. Menstruation is a physiological process manifested in rejection of the functional endomethrium layer and vaginal bleeding. Usually a women have a regular menstrual cycle. The disorders of the menstrual cycle can be caused by the hormonal changes, infectious diseases.

Pregnancy includes such issues as

  • Impregnation
  • Carrying of pregnancy and those changes that take place in the women's organism during the pregnancy
  • Act of delivery

If we talk about women's health in women over 45 years we usually talk about 2 conditions : menopause and osteoporosis. Menopause is a period in the women's health when her menstruation stops. In this period a women's organism begins to produce less sex hormones such as estrogens and progestogens. In this period many women complain on hot flashes, night sweats and others. In the period of menopause women usually relieve hormonal replacement therapy.

Another condition that is closely related to menopause is osteoporosis. Osteoporosis is a disease of the bones that becomes fragile and more susceptible to fractures. The treatment of osteoporosis includes life style changes, proper nutrition and certain medication such as Fosamax and Evista.