Generic Spiriva (Tiotropium Bromide)
Spiriva is an anticholinergic agent, it widens breathing passages and is used treat breathing difficulties caused by chronic obstructive pulmonary disease.
Per Inhalers
9 mcg x 1 inhaler
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9 mcg x 3 inhalers
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9 mcg x 6 inhalers
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Product Description
References 1. Chronic obstructive pulmonary disease COPD Spirlva approximately 16 million people and is the fourth leading cause of chronic morbidity Spiriva mortality in the USA 12. Do not Spigiva this medicine in larger or smaller amounts or for longer than recommended. Try inhaling again. Article Sources. How to Properly Use an Incentive Spirometer. In contrast, fluticasone was found to reduce the rate of deterioration compared with placebo, but the improvement was never significant. The ester tiotropium is nonenzymatically cleaved to the inactive alcohol N-methylscopine and the inactive acid compound dithienylglycolic acid 5. There were differences between the Respimat and HandiHaler study populations at baseline, including smoking status, gender, and disease severity, and the causes of death varied across studies.

Spiriva - site

Do not breathe into the mouthpiece at any time. This trial compared tiotropium with a commonly used medication in COPD, salmeterol, Spiriva included a placebo arm. The trial was well designed, with appropriate spirometric measures used to evaluate COPD severity and changes in lung capacity. The incidence of side effects was low, and dry mouth was the most common at 9. CL-SVR 2. Continuar Continue Cancelar Cancel. There are numerous possible side effects of using Spiriva that you should be aware of ranging from common to more severe. Avoid getting the powder from the Spiriva capsule into your eyes. Dosing information Spiriva Handihaler should be Spirivz every day as 2 inhalations of the powder contents Spieiva one capsule with the handler device, once daily. Spuriva is the only long-acting anticholinergic available on the market. Skip to Content. If you have any of these symptoms, stop taking the medicine and seek emergency medical care. To send another, select "Share again" below and Spirova another friend's name and Spiirva address. Spiriva is an anticholinergic drug targeted at chronic obstructive pulmonary disease COPD. Since its launch, sales of the drug have continuously increased. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Spiriva only for the indication prescribed. Close the white mouthpiece cover on the Spiriva HandiHaler device. This list is not complete. Patients who are allergic to milk proteins or any of the ingredients of the medication should not take Spiriva Handihaler and Spiriva Respimat. Email results To send your discussion guide answers to your email address, just enter your information below. Retrieved 22 December For patients in clinical trials that were treated with Spiriva Respimat, common side effects included:. You can change your cookie settings at any time. The following are more serious side effects which have been reported after using Spiriva. Tell your doctor about all your medical conditions including kidney problems, glaucoma, enlarged prostate, problems passing urine, or blockage in your bladder. Use only 1 capsule at a time. Liver insufficiency is not expected to have any relevant influence on tiotropium pharmacokinetics because the medication is cleared primarily by renal elimination and simple nonenzymatic ester cleavage to pharmacologically inactive products 5. This drug should be taken as two inhalations puffs once each day. Different interactions can cause different effects. Depending on how severe your asthma or COPD symptoms are, your doctor may recommend that you use other medications that also work over time. Taking Spiriva with other anticholinergic agents can increase your risk of side effects from the drugs. Throw away any capsule that is not used right after you have taken it out of the blister pack. But for sudden breathing problems, you should use a rescue inhaler. The number of exacerbations was 0. Exclusion criteria included a history of asthma, allergic rhinitis, or atopy; increased total blood eosinophil count; significant disease other than COPD; recent myocardial infarction, heart failure, or cardiac arrhythmia requiring medication therapy; or required oxygen therapy. Cardiovascular effects of tiotropium remain questionable. For people with asthma, it takes about 4 to 8 weeks to see the most improvement in their symptoms. The incidence of side effects was low, and dry mouth was the most common at 9. Spiriva HandiHaler and Spiriva Respimat both contain the drug tiotropium bromide, while Incruse Ellipta contains the drug umeclidinium. Note: Advair is also available in a form called Advair Respules. Major symptoms of COPD include a cough with mucus, respiratory infections, wheezing, shortness of breath and fatigue. As with most drugs, some people can have an allergic reaction after taking Spiriva. After 2 years of treatment, there were no differences in the number of COPD flare-ups seen between the two groups of people. It will take only 2 minutes to Spiriva in. Generic Side effects Dosage Alternatives Spiriva vs. The trial was well designed, with appropriate spirometric measures used to evaluate COPD severity and changes in lung capacity. Spiriva overdose. Here we look at how Spiriva and Incruse Ellipta are alike and different. Available for Android and iOS devices. Alternatives to Spiriva. The oxygen passes through the air sacs and then into the blood. The safety and effectiveness of tiotropium have not been established in children, and therefore the drug should not be used in patients younger than 18 years 5. Before taking Spiriva, talk with your doctor about your health history. A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patients treated with tiotropium or salmeterol. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Spiriva only for the indication prescribed. Unfortunately, a power analysis was not presented, so neither the appropriateness of the sample size nor the reasoning for distributing two thirds of the patients in the tiotropium group and one third in the ipratropium group could be determined. Available for Android and iOS devices. Spiriva precautions. National Center for Biotechnology InformationU.

Common use

Spiriva is a specific antagonist of muscarinic receptors with longterm action. It reversibly blocks receptors of M3 type in respiratory track which results in relaxation of smooth muscles of the bronchial tree. High affinity of the receptors and slow release of the inhibitor from the complex with M3 receptor stipulates prolonged local action of Tiovais. Bronholitic effect of the drug results of local action, dose and persisted for at least 24 hours. Effects of Spiriva depend on the dose and continues for 24 hours. The medication is used to treat bronchial spasms (wheezing) caused by chronic obstructive pulmonary disease, chronic bronchitis and emphysema.

Dosage and direction

Spiriva comes as capsules with powder for inhalations with the HandiHaler inhalation device. Use the medication about the same time each day.


Cautiousness is needed in treatment of patients with narrow-angle glaucoma, urination disorders caused by prostatic hypertrophy or obstruction of the bladder neck. Tiovais cannto be used for urgent blockage of a bronchial spasm. Avoid getting of the medication in eyes. Monitoring on a regular basis is needed in the patients with moderate and severe renal failure treated by Tiovais and medications which excreted by the kidneys. Inhaled medications may cause paradoxical bronchospasm and other reactions of such kind. Avoid administration of the medication if you are pregnant or breastfeeding.


Spiriva cannot be administered to the patients with hypersensitivity to the medication, atropine and its derivates (ipratropium and oxytropine). Use in adolescents under 18 years of age is not researched.

Possible side effects

Most common side effects include local reactions such as dry mouth, throat pain, coughing, paradoxical bronchospasm. Changes in accommodation if the medication got into the eyes. Allergic reactions (rash, swelling) are possible. In rare were observed cases short heart beat, acute glaucoma, difficulty urination in men with prostatic hypertrophy, constipation.

Drug interactions

Concomitant use of Spiriva with other anticholinergetic medications is not recommended.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your doses at about the same time each day to avoid missing a dose.


It was not reported about overdose if Spiriva was used in therapeutic doses. In case of considerable exceeding of the recommended dose symptoms associated with anticholinergetic properties of the medication are observed: reversible changes in accommodation, dry mouth. Acute poisoning is not likely due to low biological availability of the medication used as inhalations.


Store at room temperature away from moisture, sunlight, kids and pets in a tight container.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Women's Health

Talking about women's health we usually mean a number of issues that are associated with women's physiology and anatomy. These issues usually includes gynecological diseases, pregnancy and breastfeeding, menopause, contraception and diseases that are peculiar only to women sex.

Gynecological diseases usually includes infectious diseases that are transmitted through the sexual intercourse. These may be viral, bacterial or fungal infection. The gynecological infections usually manifest in the form of inflammation, edema, redness, itching, discharges, pain in the pelvic area.

Menstruation, pregnancy and breastfeeding are related to the women's reproductive system. Menstruation is a physiological process manifested in rejection of the functional endomethrium layer and vaginal bleeding. Usually a women have a regular menstrual cycle. The disorders of the menstrual cycle can be caused by the hormonal changes, infectious diseases.

Pregnancy includes such issues as

  • Impregnation
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  • Act of delivery

If we talk about women's health in women over 45 years we usually talk about 2 conditions : menopause and osteoporosis. Menopause is a period in the women's health when her menstruation stops. In this period a women's organism begins to produce less sex hormones such as estrogens and progestogens. In this period many women complain on hot flashes, night sweats and others. In the period of menopause women usually relieve hormonal replacement therapy.

Another condition that is closely related to menopause is osteoporosis. Osteoporosis is a disease of the bones that becomes fragile and more susceptible to fractures. The treatment of osteoporosis includes life style changes, proper nutrition and certain medication such as Fosamax and Evista.