Generic Compazine (Prochlorperazine)
Compazine
Compazine is used to treat psychotic disorders such as schizophrenia, and in anti-emetic treatment of nausea and vertigo.
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Product Description

Compazine - the purpose

Interactive Compazins. Copyright and License information Disclaimer. Arms and Interventions. Common side effects include sleepiness, blurry vision, low Compzzine pressureand dizziness. Contacts and Locations. NHS Choices. Learn about the Compazine side effects, related class drugs, and how these medications will affect your daily lifestyle. Prochlorperazine10H-Phenothiazine, 2-chloro 3- 4-methylpiperazinyl propyl -Prochlorperazine [antipsych]Prochlorperazine [antipsych] [see dhe. Randomized, placebo-controlled evaluation of prochlorperazine versus metoclopramide for emergency department treatment of migraine headache. Related Topics in Pharmacology. Can Psychiatr Assoc J. J Emerg Med. Intranasal ketamine for analgesia in the emergency department: a prospective observational series. For general information, Learn About Clinical Studies. Positive values represent a reduction in headache severity. Phenothiazine antiemetics Phenothiazine antipsychotics. Information from the National Library of Medicine To learn more about this Compazibe, you or your doctor may contact the study research staff using the contact information provided by Comppazine sponsor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. Neither Everyday Health nor its licensors endorse drugs, diagnose patients or recommend therapy. Agonists: 4-Methylaminorex Aminorex Amphetamines e. Prochlorperazine Interactions. Prochlorperazine maleate is not approved for the treatment of patients with dementia-related psychosis. It is not as commonly prescribed as it used to be because many gastroenterologists are now using newer anti-nausea medications. The electronic medical record order will read "randomized study medication" for the Ketamine or prochlorperazine and "randomized add-on medication" for the ondansetron or diphenhydramine. Frequency not reported : Hyponatremiahyperglycemia, hypoglycemiaincreased appetite, increased weight, impaired glucose tolerance [ Ref ]. Is a prisoner Patient declined informed consent Non-English speaking patient. Views Read Edit Compazins history. Using this medicine with any of the following may cause an increased Compazine of certain side effects but may be unavoidable in some cases. A variant of tardive dyskinesia, tardive Comoazine, has also been described. Images: Related links to external sites from Bing. The following are signs of neuroleptic malignant syndrome and should be checked out immediately. Thanks for your feedback! Frequency not reported : Endocrine disturbances, syndrome of inappropriate antidiuretic hormone secretion SIADHfalse-positive pregnancy tests [ Ref ]. Hide glossary Glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information. Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache. Tardive dyskinesia. Pharmacology Chapter. Non-Psychotic Anxiety — Usual dosage is 5 mg 3 or 4 times daily. Last Update Posted : December 11, For general information, Learn About Clinical Studies. Product Information. Some symptoms of NMS include high fever, stiff muscles, neck muscle spasm, confusion, irregular pulse or Compazibe pressure, fast Copmazine rate tachycardiasweating, abnormal heart rhythms arrhythmias. This information is provided only to help medical providers and their patients see relative costs. EKG changes - particularly nonspecific, usually reversible Q and T wave distortions — have been observed in some patients receiving phenothiazines. Please refer to this study by its ClinicalTrials. MedlinePlus related topics: Headache. J Natl Med Assoc. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. NHS Choices. Antagonists: Metitepine methiothepin. Frequency not reported : Endocrine disturbances, syndrome of inappropriate antidiuretic hormone secretion SIADHfalse-positive pregnancy tests [ Ref ].
Common use

Compazine is an anti-psychotic medication which used to treat psychotic disorders such as schizophrenia. Also Compazine used to control severe nausea and vomiting and to treat anxiety. Compazine changes the actions of chemicals in your brain. Compazine is usually used as tranquilizer and antipsychotic drug.



Dosage and direction

Take it orally with a full glass of water, with or without food or milk.

The recommended dose for adults depend from type of disease:

To Control Severe Nausea and Vomiting

The usual dosage is one 5-milligram or 10-milligram tablet 3 or 4 times a day.

For Non-psychotic Anxiety

The usual dose is 5 milligrams, taken 3 or 4 times a day.

Relatively Mild Schizophrenia

The usual dose is 5 or 10 milligrams, taken 3 or 4 times daily.

Moderate to Severe Schizophrenia

Dosages usually start at 10 milligrams, taken 3 or 4 times a day.

More Severe Schizophrenia

Dosages may range from 100 to 150 milligrams per day.

The recommended dose for children also depends from type of disease, weight and their age:

Children under 2 years of age or weighing less than 20 pounds should not be given Compazine.

For Severe Nausea and Vomiting

An oral of Compazine is usually not needed for more than 1 day.

Children 20 to 29 Pounds

The common dose is 2-0.5 mg 1 or 2 times daily. Do not give over 7.5 mg daily.

Children 30 to 39 Pounds

The usual dose is 2-0.5 mg 2 or 3 times daily. Do not give over 10 mg daily.

Children 40 to 85 Pounds

The usual dose is 2-0.5 mg 3 times daily, or 5 mg 2 times daily. Do not give over 15 mg.

For Psychotic Disorders

Children 2 to 5 Years Old

The starting oral or rectal dose is 2-0.5 mg 2 or 3 times daily. Do not give over 10 mg the first day and 20 mg thereafter.

Children 6 to 12 Years Old

The starting oral or rectal dose is 2-0.5 mg 2 or 3 times daily. Do not give over 10 mg the first day and 25 mg thereafter.

The recommendation for older adults:

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.





Precautions

Use Compazine with cautions in people with hepatic or renal disease, glaucoma, prostatic hypertrophy, severe asthma, prolonged use, cardiovascular disease, epilepsy. Do not use in children under 5 years age. Compazine should not be used during pregnancy, becoming pregnant or lactating without doctor's advice.Do not use Compazine before breast-feeding without doctor's permission.

Contraindications

Compazine is not allowed to people who are hypersensitive to any components of this drug. Contraindicated in people with severe toxic CNS depression, coma, subcortical brain damage, bone marrow depression,severe liver or cardiac disease, narrow-angle glaucoma, pediatric surgery.



Possible side effect

They may include call types of an allergic reaction. Also the most possible side effects include:

twitching or uncontrollable movements of your eyes, tongue, lips, face, arms, or legs;

tremor, drooling, trouble swallowing, problems with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling like you might pass out;

seizure (black-out or convulsions);

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

nausea and stomach pain, skin rash, and jaundice (yellowing of the skin or eyes);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

urinating less than usual or not at all;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color;

slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious include:

dizziness, drowsiness, anxiety;

sleep problems (insomnia), strange dreams;

dry mouth, stuffy nose;

blurred vision;

constipation;

breast swelling or discharge;

a missed menstrual period;weight gain, swelling in your hands or feet;

impotence, trouble having an orgasm;

mild itching or skin rash;

headache.

If you experience one of them stop using Compazine and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Sympotms of Compazine overdose may include dry mouth, constipation, bloating or stomach cramps, extreme drowsiness or feeling restless and agitated, changes in heart rate, fever, and fainting. If you experience one of them or any unusual symptoms call your doctor immediately.



Storage

Store at room temperature between 20-25 C (68-77 F).



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Women's Health

Talking about women's health we usually mean a number of issues that are associated with women's physiology and anatomy. These issues usually includes gynecological diseases, pregnancy and breastfeeding, menopause, contraception and diseases that are peculiar only to women sex.

Gynecological diseases usually includes infectious diseases that are transmitted through the sexual intercourse. These may be viral, bacterial or fungal infection. The gynecological infections usually manifest in the form of inflammation, edema, redness, itching, discharges, pain in the pelvic area.

Menstruation, pregnancy and breastfeeding are related to the women's reproductive system. Menstruation is a physiological process manifested in rejection of the functional endomethrium layer and vaginal bleeding. Usually a women have a regular menstrual cycle. The disorders of the menstrual cycle can be caused by the hormonal changes, infectious diseases.

Pregnancy includes such issues as

  • Impregnation
  • Carrying of pregnancy and those changes that take place in the women's organism during the pregnancy
  • Act of delivery

If we talk about women's health in women over 45 years we usually talk about 2 conditions : menopause and osteoporosis. Menopause is a period in the women's health when her menstruation stops. In this period a women's organism begins to produce less sex hormones such as estrogens and progestogens. In this period many women complain on hot flashes, night sweats and others. In the period of menopause women usually relieve hormonal replacement therapy.

Another condition that is closely related to menopause is osteoporosis. Osteoporosis is a disease of the bones that becomes fragile and more susceptible to fractures. The treatment of osteoporosis includes life style changes, proper nutrition and certain medication such as Fosamax and Evista.