Generic Danazol
Danazol
Danazol is a synthetic steroid hormone used in treatment of endometriosis, fibrocystic breast disease, benign breast tumors, abnormally long periods, premenstrual syndrome, gynecomastia.
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50 mg x 30 pills
$163.99
$5.47
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50 mg x 60 pills
$273.99
$4.57
$54.00
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50 mg x 90 pills
$373.99
$4.16
$117.90
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100 mg x 30 pills
$199.99
$6.67
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100 mg x 60 pills
$333.99
$5.57
$66.00
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100 mg x 90 pills
$454.99
$5.06
$144.90
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200 mg x 30 pills
$307.99
$10.27
$0.00
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200 mg x 60 pills
$603.99
$10.07
$12.00
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200 mg x 90 pills
$897.99
$9.98
$26.10
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Product Description
Elks 14 November Take the missed dose as soon as you remember. However, many people have no Danazol effects or only have minor side effects. CRC Press. Subscribe to Drugs. AvKare, Inc. Tell your doctor about any such situation that affects you. Sedef Iskit. Retrieved 27 June While using danazol, you may need blood tests at your doctor's office. Ampio Pharmaceuticals. Drug Class. Explore now. Ask your pharmacist for a list of the ingredients. This is not a complete list of side effects and others may occur. Screening Tests. Danazol is known to bind to two steroid hormone carrier proteins: sex hormone-binding globulin SHBGwhich binds androgens and estrogens ; and corticosteroid-binding globulin CBGwhich binds progesterone and cortisol. Related Drugs.

Danazol - for explanation

Risk Factors. Store it at room temperature and away from light and excess heat and moisture not in the bathroom. Distribution: Unknown. There is a risk of long-term Danocrine treatment causing liver damage. Interactive image. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. I accept the Terms and Privacy Policy. You are viewing BNF. Tell your doctor about any such situation that affects you. An overdose of danazol is not expected to produce life threatening symptoms. Tell your doctor if you have or have ever had liver disease. Pediatric Supportive Care. It is not known if danazol is excreted in the breastmilk nor whether it has harmful effects on the infant. If you experience any of the following symptoms call your doctor immediately: warm, red, swollen, or tender leg; trouble speaking or understanding; paralysis or numbness in face, arm or leg; sudden severe headache; sudden changes in vision, blurred or blackened vision, or seeing double. In case of overdose, call the poison control helpline at It works to treat fibrocystic breast disease by blocking the release of hormones that cause the breast pain and lumps. Do not take more or less of it or take it more often than prescribed by your doctor. Call your doctor for medical advice about side effects.
Common use

Danazol is a synthetic steroid produced from ethisterone. This medication suppresses synthesis of

gonadotrophic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by pituitary gland in men and women. In women this drug inhibits activity of the ovaries, ovulation, leads to atrophy of the endometrium. The medication is used to treat to treat endometriosis (associated with sterility), fibrocystic breast disease, to prevent attacks of inherited angioedema, benign breast tumors (fibro-cystic breast), menorrhagia (abnormally heavy and prolonged menstrual period), premenstrual syndrome, primary premature puberty, gynecomastia.



Dosage and direction

The common recommended dose in adults is 200-800 mg a day divided in 2-4 intakes. Treatment starts on the first day of the menstrual cycle. To treat severe endometriosis the initial daily dose is 400 mg, later the dose may be increased to 800 mg by your physician. Treatment continues for six months. In children with premature puberty the dose is 100-400 mg.



Precautions

Cautiousness should be exercised in patients with diabetes mellitus, epilepsy, migraine. Use reliable and effective forms of contraception while you are on Danazol such as a condom or diaphragm with spermicide gel or inserts as hormonal forms of contraception may turn out non effective. Dose correction is needed in patients with diabetes. Take this drug according to the instructions of your doctor. Do not exceed the recommended dose. Women may need to start Danazol during their menstrual period. This medication may change results of some medical tests, inform your doctor if you take this medication. Do not start or stop this medication without approval of your doctor, continue to take it even if you do not notice immediate positive results of treatment. If your symptoms do not improve in two months inform your doctor.



Contraindications

This medication cannot be used in patients with hypersensitivity to Danazol or its components, in pregnant and breastfeeding women, porphyria (activity of liver transaminases increases), liver or kidney failure, chronic heart failure, thromboembolism, androgen producing tumor, vaginal bleeding of unknown origin.



Side effects

The most common side effects include signs of allergy (hives, rash, facial swelling, difficulty breathing) and also sudden numbness or weakness, angina, sudden cough, wheezing, rapid breathing, fast heart rate, sudden problems with vision, speech, or balance, confusion, swelling, feeling short of breath, rapid weight gain, headache, vision problems, ringing in the ears, dizziness, nausea, loss of appetite, dark urine, pain behind the eyes, stomach pain, jaundice.



Drug interaction

Danazol increases effects of anticoagulants of cumarine series and derivatives of indandione such as the risk of bleeding. Danazol decreases effects of insulin and oral hypoglycemic drugs by affecting metabolism of carbohydrates, increasing blood sugar levels Danazol inhibits metabolism of carbamazepine and increase its blood levels increases blood concentrations of cyclosporine and tacrolimus hereby increasing risk of nephrotoxicity. Danazol also increases serum levels of glucagon.



Missed dose

Take the missed dose as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule. Do not double dose this medication to make up the missed dose.



Overdose

This medication is not likely to produce life-threating symptoms. The most common effects of overdose are weight gain, menstrual problems, increased acne or facial hair growth, breast changes.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Women's Health

Talking about women's health we usually mean a number of issues that are associated with women's physiology and anatomy. These issues usually includes gynecological diseases, pregnancy and breastfeeding, menopause, contraception and diseases that are peculiar only to women sex.

Gynecological diseases usually includes infectious diseases that are transmitted through the sexual intercourse. These may be viral, bacterial or fungal infection. The gynecological infections usually manifest in the form of inflammation, edema, redness, itching, discharges, pain in the pelvic area.

Menstruation, pregnancy and breastfeeding are related to the women's reproductive system. Menstruation is a physiological process manifested in rejection of the functional endomethrium layer and vaginal bleeding. Usually a women have a regular menstrual cycle. The disorders of the menstrual cycle can be caused by the hormonal changes, infectious diseases.

Pregnancy includes such issues as

  • Impregnation
  • Carrying of pregnancy and those changes that take place in the women's organism during the pregnancy
  • Act of delivery

If we talk about women's health in women over 45 years we usually talk about 2 conditions : menopause and osteoporosis. Menopause is a period in the women's health when her menstruation stops. In this period a women's organism begins to produce less sex hormones such as estrogens and progestogens. In this period many women complain on hot flashes, night sweats and others. In the period of menopause women usually relieve hormonal replacement therapy.

Another condition that is closely related to menopause is osteoporosis. Osteoporosis is a disease of the bones that becomes fragile and more susceptible to fractures. The treatment of osteoporosis includes life style changes, proper nutrition and certain medication such as Fosamax and Evista.