Generic Epivir (Lamivudine)
Epivir is an antiviral medication used to fight infection with the human immunodeficiency virus (HIV), the deadly cause of AIDS.
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Product Description

Epivir - confirm. And

Daily news summary. Further reading and references. Remember, keep this and all other medicines out of the reach of children, never share your medicines with Epivir, and use Epivir only for the indication prescribed. Please visit our new site at hivandhepatitis. It is given alongside a number of other antiretroviral medicines, as part of a combination therapy. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: AIDS defining condition within 1 month of study entry. Uncommon side effects These may affect up to 1 in people: Uncommon side effects that may show up in blood tests are: a decrease in the number of cells involved in blood clotting thrombocytopenia a low red blood cell count anaemia or low white blood cell count neutropenia an increase in the level of liver enzymes. Call your doctor for medical advice about side effects. From Wikipedia, the free encyclopedia. Epivir was approved in as the fourth antiretroviral medication and nuke. Jump to navigation. Epivir, or lamivudine, is the oldest antiretroviral still in use today. You seem to have a popup blocker enabled. Subsequently, lamivudine was studied in combination with another NRTI plus an early protease inhibitor or NNRTI for 3-drug therapy and found to be effective at achieving virologic suppression; for example, lamivudine was studied in combination with zidovudine and efavirenz [ GS ], as well as with abacavir and either ritonavir-boosted fosamprenavir [ KLEAN ] or lopinavir [ HEAT ]. Clinical manifestations and management of antiretroviral nucleoside analog-related mitochondrial toxicity. Share Print. HBV should be closely monitored by your provider. Health Tools Feeling unwell? The combination of dolutegravir and lamivudine is effective for treatment-naive patients regardless of age, gender, or race, according to a new subgroup analysis of the GEMINI clinical studies. See package insert for guidance on dosing in the setting of kidney impairment. Click here to log back in. Taking a combination of different medicines also reduces the risk that the virus will become resistant to any individual medicine. Instead, the best way to dispose of your medication is through a medicine take-back program. World Journal of Hepatology. People Epivvir combination therapy for HIV may find that their body shape changes, because of changes in fat distribution:. Mothers taking the Epivir combination gave birth to HIV-infected babies only one-half of 1 percent of the time in the 3,women, randomized study. This includes prescription and over-the-counter medicines, vitaminsand herbal products. More Information. Epivir Epvir approved for the treatment of HIV by the U. Mutation at codon may reverse resistance associated with thymidine analogues and tenofovir. Looking to lose weight this year? Click here to Epivur back in. Epivir lamivudine is an antiviral medicine that prevents human immunodeficiency virus HIV or hepatitis B virus from multiplying in your body. Epivvir symptoms are probably Epivir by the body? After being diagnosed with HIV, David faced several challenges and reactions rooted in stigma and misinformation when dating. Poor virologic responses and early emergence of resistance in treatment naive, HIV-infected patients receiving a once daily triple nucleoside regimen of didanosine, lamivudine, and tenofovir DF. Do not take Epivir after the expiry date shown on the carton. Sharing drug or medicine needles is never safe, even for a healthy person. Talk to your doctor if any of these apply to you. Adverse Effects Overall, lamivudine tends to be well tolerated. Implications of lamivudine resistance for treatment with other antiretrovirals Laboratory strains of HIV resistant to lamivudine by virtue of a mutation at codon show resistance to emtricitabine and may show resistance to abacavir and didanosine. You may have problems with your bones Some people taking combination therapy for HIV develop a condition called osteonecrosis. Characteristics of NRTIs. It is therefore essential to assess patient motivation and discuss possible side effects and strategies for their management before any regimen containing lamivudine is initiated. Site Navigation. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomitingirregular heart rate, dizziness, feeling cold, or feeling very weak or tired. Do not let anyone else take your medication. Some people taking Epivir, or other medicines like it NRTIsdevelop a condition called lactic acidosis, together with an enlarged liver. You may have problems with your bones Some people taking combination therapy for HIV develop a condition called osteonecrosis. The active substance is lamivudine. Epivir Usage Back to Top. Epivir is available as a single drug or in the fixed-dose combination drugs Combivir, Epzicom, Triumeq, and Tirizivir.

Same: Epivir

VP-GL Tel 21 08 01 viiv. You should stay under the care of a doctor during treatment so you can be checked for possible serious side effects. Dated February Monitor for treatment-associated toxicities esp. TRIM5alpha gene. Very rare side effects These may affect up to 1 in 10, people: tingling or numbness of the arms, legs, hands or feet. Related Drugs. Never give it to other people even if their condition appears to be the same as yours. Tell your doctor if you. Failure of combination regimens containing lamivudine may be associated with viral resistance to lamivudine without detectable resistance to other components of the antiretroviral regimen. Uncommon side effects These may affect up to 1 in people: Uncommon side effects that may show up in blood tests are: a decrease in the number of cells involved in blood clotting thrombocytopenia a low red blood cell count anaemia or low white blood cell count neutropenia an increase in the level of liver enzymes. Common lamivudine side-effects these affect less than 1 in 10 people. Keep all appointments with your doctor and the laboratory. Rare side effects These may affect up to 1 in people: serious allergic reaction causing swelling of the face, tongue or throat which may cause difficulty in swallowing or breathing lactic acidosis see the next section. Send us your comments by March 14.
VIBRAMYCIN Epivir very rare side effect that may show up in blood tests is: a failure of the bone marrow to produce new red blood cells pure red cell aplasia. Side Effects The most common side effects caused by drug regimens containing Epivir are headache, diarrhea, and nausea. No significant drug interactions. Categories : Hepatotoxins Nucleoside analog reverse transcriptase inhibitors World Health Organization essential medicines Nucleosides Pyrimidones. Do not double up on your next dose. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Back to Drug Profiles. Mengla virus MLAV. I accept the Terms and Privacy Policy. In this article About lamivudine Before taking lamivudine How to take lamivudine Getting the most from your treatment Can lamivudine cause problems. Standard Dose One mg tablet once daily or one mg tablet twice dailywithout regard to food. Epivir contains a higher dose of lamivudine than Epivir-HBV. Recommended as component of initial regimen for most people when used in combination with dolutegravir and abacavir. Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Special Uses Lamivudine is active against hepatitis B virus, but resistant HBV is observed to emerge over months in the setting of treatment with lamivudine alone. To protect other people from becoming infected with HIV: Use a condom when you have oral or penetrative sex. Patients with Renal Impairment Dosage recommendations for adult patients with reduced renal function are provided in Table 1 [see Clinical Pharmacology With this condition, parts of the bone tissue die because of reduced blood supply to the bone.
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You should, however, speak Epkvir your doctor if you Epivit any of the following side-effects. Tell your doctor or pharmacist if you? Children with prior antiretroviral nucleoside exposure, history of pancreatitis or risk factors for pancreatitis. Very rare side effects Epivir may affect up to 1 in 10, people: tingling or numbness of the arms, legs, hands or feet. TruvadatenofovirentecavirlamivudineabacavirAtriplaVireadVemlidyBaracludeStribild. Epivir dosage information in more detail. How should it be stored? Lipshultz found that while none of the HIV-exposed but uninfected children were sick from heart disease between two and seven years later, some had impaired heart muscle structure and function after being exposed to the medications. Tell your doctor immediately. If you become pregnant while you? Take Epivir exactly as prescribed by your doctor. This medication may be prescribed for other uses. Italia ViiV Healthcare S. You can take your doses either before or after meals. Interactions: Avoid concomitant sorbitol-containing products. Before taking this medication, tell your doctor if you have kidney disease or liver disease.
Common use

Epivir is an antiviral medication which used to fight infection with the human immunodeficiency virus (HIV), the deadly cause of AIDS. Epivir prevents the cells from producing new virus and decreases the amount of virus in the body. This drug is also prescribed for the treatment of chronic hepatitis B infection. Note that this medication must be used in combination with other HIV drugs.

Dosage and direction

Take it orally with or without food/milk at the same time each day. The Epivir dose normally used to treat hepatitis B for adults is one 100mg tablet once a day. The recommended dosage for treatment HIV is one 300mg tablet once daily or one 150mg tablet every 12 hours.

Children dosage depends on the weight of the child, and their ability to swallow pills. The liquid formulation should be given 4 mg per kilogram of body weight, up to a maximum of 150 milligrams twice daily.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.


Do not take it without doctor's permission if your medical history include: kidney disease; liver disease; pancreatitis; problems with your muscles; or problems with your blood counts. Remember that this drug does not reduce the risk of passing the HIV or hepatitis B virus to others. Do not use alcohol because it may increase the risk of damage to the pancreas and/or liver. Epivir should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Epivir before breast-feeding without doctor's advice.


Epivir is not allowed in people who are hypersensitivity to the active substance or to any of the excipients.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:

liver damage, stomach pain, clay-colored stools, low fever, loss of appetite, dark urine, jaundice; muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, and fast or uneven heart rate; pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; peripheral neuropathy - numbness, tingling, or pain in your hands or feet; easy bruising or bleeding, unusual weakness, pale skin; white patches or sores inside your mouth or on your lips; fever, chills, body aches, flu symptoms; any other signs of new infection.

Less serious include:

cough; sleep problems (insomnia), strange dreams; nausea, vomiting, diarrhea; joint or muscle pain;

dizziness, headache, tired feeling; changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).

If you experience one of them stop using Epivir and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Epivir interact with interferon-alfa (Roferon, Intron, Rebetron); trimethoprim (Bactrim, Proloprim, Septra, Trimpex); or ribavirin (Rebetol, Ribasphere, Copegus Virazole). Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.


Symptoms of Epivir overdose are not known. So if you experience any unusual symptom call your doctor immediately.


Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Women's Health

Talking about women's health we usually mean a number of issues that are associated with women's physiology and anatomy. These issues usually includes gynecological diseases, pregnancy and breastfeeding, menopause, contraception and diseases that are peculiar only to women sex.

Gynecological diseases usually includes infectious diseases that are transmitted through the sexual intercourse. These may be viral, bacterial or fungal infection. The gynecological infections usually manifest in the form of inflammation, edema, redness, itching, discharges, pain in the pelvic area.

Menstruation, pregnancy and breastfeeding are related to the women's reproductive system. Menstruation is a physiological process manifested in rejection of the functional endomethrium layer and vaginal bleeding. Usually a women have a regular menstrual cycle. The disorders of the menstrual cycle can be caused by the hormonal changes, infectious diseases.

Pregnancy includes such issues as

  • Impregnation
  • Carrying of pregnancy and those changes that take place in the women's organism during the pregnancy
  • Act of delivery

If we talk about women's health in women over 45 years we usually talk about 2 conditions : menopause and osteoporosis. Menopause is a period in the women's health when her menstruation stops. In this period a women's organism begins to produce less sex hormones such as estrogens and progestogens. In this period many women complain on hot flashes, night sweats and others. In the period of menopause women usually relieve hormonal replacement therapy.

Another condition that is closely related to menopause is osteoporosis. Osteoporosis is a disease of the bones that becomes fragile and more susceptible to fractures. The treatment of osteoporosis includes life style changes, proper nutrition and certain medication such as Fosamax and Evista.