Generic Zetia (Ezetimibe)
Zetia
Zetia is used to treat high cholesterol in combination with low fat diet.
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10 mg x 30 pills
$49.99
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10 mg x 60 pills
$80.99
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10 mg x 90 pills
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10 mg x 120 pills
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10 mg x 180 pills
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Product Description

Above: Zetia

Malegra DXT Retrieved 15 July Articles from Proceedings Baylor Zetiw. The primary efficacy Zetiia was the effect of Zftia on the intestinal absorption of cholesterol. When the F. This leads to a reduction of hepatic cholesterol stores and an increase in clearance of cholesterol from the blood. Due to unknown effects of increased exposure, ezetimibe is Zteia recommended in patients with moderate-to-severe hepatic insufficiency. The treatment groups were the Zetka 1 ezetimibe 10 mg monotherapy, 2 ezetimibe 10 mg in combination with simvastatin, or mg, 3 simvastatin, or mg monotherapy, and 4 placebo. Corresponding author. The study consisted of 2 phases: a 6- to week open-label, nonrandomized statin atorvastatin 40 mg or simvastatin 40 mg lead-in phase and a week study phase during which patients were randomized to receive 1 of 3 once-daily double-blind treatments: statin 80 mg, ezetimibe 10 mg plus statin 40 mg, or ezetimibe 10 mg plus statin 80 mg. Ezetimibe 10 mg daily may be given with or without food along with a standard cholesterol-lowering diet. The authors concluded that ezetimibe was well tolerated and possesses a safety profile similar to simvastatin and placebo. Also, the combination of ezetimibe and lovastatin has no greater adverse effects than lovastatin monotherapy 7. Study results were based on an intent-to-treat analysis. However, this study was conducted for a period of only 8 weeks, which might not be long enough to reveal the full benefits of the drug.
IMODIUM Due to once-daily dosing and limited side effects, compliance should not be a major concern. Statin contraindications also apply when ZETIA is used with these drugs: statins are contraindicated in patients with active liver disease, unexplained persistent elevations in hepatic transaminase levels and Zetia pregnant and nursing women. The risk of myopathy, including rhabdomyolysis, is dose related. Take the missed dose as soon as you remember. Any unexplained muscle pains or aches, tenderness, or weakness should be reported to a health care provider as soon as possible, as these may be signs of a rare, but serious condition known as rhabdomyolysis. Moreover, nine patients in the Zetia arm had heart attacks, stroke, or died from heart disease, versus just two patients taking niacin. Zetia may not be as effective as statin drugs lovastatin, simvastatin, pravastatin, and others in lowering cholesterol. References 1.
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Overall, when ezetimibe was added Zftia simvastatin, there was an Zetia Zettia cholesterol medications should not be taken at the same Zeia. Call your doctor for medical advice about side effects. A: Numbness and pinprick-like pain could be a side effect of Zetia Ezetimibewhich you are taking. Currently, no dosage adjustment is Zetiz in renal insufficiency. I have been on it for two weeks and I have been experienced painful Zetiaa in both legs, arms, hands and painful itching all over my body. An overdose of Zetia should not produce life-threatening symptoms, but seek emergency medical help if you think you have overdosed. Zetia may not be as effective as statin drugs lovastatin, simvastatin, pravastatin, and others in lowering cholesterol. Patients were excluded from the study if they received lipid-lowering drugs within 6 weeks of study entry, had a history of excessive alcohol intake, had diabetes or other endocrine disorders, had a history of hepatic disease, or gastrointestinal tract dysfunction or renal dysfunction. Your doctor needs to know about any allergies you have, and about all the medications you take, whether prescription or over-the-counter, vitaminsillegal or recreational drugs, and dietary or herbal supplements, as they can affect how Zetia works, and vice-versa. About About Drugs. Zetia ezetimibe is not a statin. These generic products are considered to be equivalent to the brand name product once evaluated and approved by the U. Gemfibrozil Lopid or cyclosporine Neoral can increase blood levels of Zetia, so watch for side effects if taken together. Do not take more than one dose of Zetia a day. Neither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information provided. Talk to Zrtia doctor or pharmacist if you are having trouble paying for your medication. You may need frequent blood tests to check your liver function if you take ezetimibe with a statin medicine. Ezetimibe coadministered Zetia Zetla or simvastatin vs statin monotherapy This multicenter double-blind, parallel-group study was done to evaluate the efficacy, tolerability, and safety of ezetimibe as an adjunct to diet and statins atorvastatin or simvastatin with or without LDL cholesterol apheresis. Also, Zehia study failed to mention LDL cholesterol reduction percentages for the different doses of simvastatin and atorvastatin used. Still, there's no denying that the higher the dose, the greater the risk of side effects. The Food and Drug Administration approved ezetimibe on October 25, 2. Ezetimibe is indicated in the United States as an add-on to dietary measures to reduce levels of certain lipids in people with: [16]. Ezetimibe improves the non-alcoholic fatty liver disease activity score but the available evidence indicates it does not improve outcomes of hepatic steatosis. Find articles by Jigna Patel. Increases in HbA1c and fasting serum glucose levels have been reported with statins, including simvastatin. What to do if you miss a dose: Take your dose as soon as you remember. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Inwhen Merck's brand of simvastatinknown as Zocor, was about to go off patent, Merck teamed up with Schering-Plough to produce a new patented product called Vytorin, a combination of simvastatin and Zetia. Do not take this medicine in larger or smaller amounts or for longer than recommended. By mouth tablets. Alirocumab Bococizumab Evolocumab. Bempedoic acid. Cutting back on the cholesterol you eat is helpful, too. Patients should be advised to promptly report muscle pain, tenderness, or weakness. It Zetiz a prescription product that has a special timed-release formulation, which may cut down Zetla the hot flashes that are associated with niacin use. Take Zetia exactly as ZZetia was prescribed for you. When used as monotherapy, the most commonly reported adverse effect is back pain 4. All rights reserved. Unlike other Ztia agents, ezetimibe works by selectively inhibiting the intestinal absorption of cholesterol and related phytosterols. External link. Furthermore, there is no inhibition of cholesterol synthesis in the liver or increase in bile acid secretion. Make a Donation Newsletters Give a Gift. No dose adjustment is needed in patients with chronic kidney disease or mild hepatic dysfunction Child-Pugh score 5—6. ZETIA should be used in pregnant or nursing women only if the benefit outweighs the risk. Q: Could Zetia cause numbness and pinprick-like pain in my thighs? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Take the missed dose as soon as you remember. Author information Copyright and License information Disclaimer. Due to insufficient data, the manufacturer does not recommend ezetimibe for patients with moderate to severe hepatic impairment Child-Pugh score 7— Zetia will not be as effective in lowering Zetiia cholesterol if you do not follow a cholesterol-lowering diet plan. Overall, ezetimibe appears to be effective in the treatment of hyperlipidemia. This condition Zetua be more likely to occur in older adults and in Zeetia who have kidney disease or poorly controlled hypothyroidism underactive thyroid. Other drugs may interact with Zetia, including prescription and over-the-counter medicines, vitamins, and herbal Zetka. Zetia Zetua interactions in more detail. Related Drugs. In turn, to produce more bile acids, the liver breaks down cholesterol. It blocks the critical mediator of cholesterol absorption, the Niemann-Pick C1-like 1 NPC1L1 protein on the gastrointestinal tract epithelial cells, as well as in hepatocytes ; it blocks aminopeptidase N and interrupts a caveolin 1 — annexin A2 complex involved in trafficking cholesterol. The two contraindications to taking ezetimibe are a previous allergic reaction to it, including symptoms of rash, angioedemaand anaphylaxisand severe liver disease, especially when taken with a statin. See also: Zetia side effects in more detail. The recommended dose of ezetimibe is 10 mg administered by mouth once daily. Zetia can be used alone or in combination with other cholesterol medications, such as statins or fenofibrate. Also, the study failed to mention LDL cholesterol reduction percentages for the different doses of simvastatin and atorvastatin used. While your at cholesterolscore. More specifically, the co-administration of ezetimibe and simvastatin mean baseline direct LDL: Updated November 18, Zetia may be used alone or in combination with other cholesterol-lowering drugs. I accept the Terms and Privacy Policy. And without data to prove that Zetia actually reduces heart attacks, doctors cannot be sure they are helping patients when they prescribe the drug, she said. It blocks the critical mediator of cholesterol absorption, the Niemann-Pick C1-like 1 NPC1L1 protein on the gastrointestinal tract epithelial cells, as well as in hepatocytes ; it blocks aminopeptidase N and interrupts a caveolin 1 — annexin A2 complex involved in trafficking cholesterol. But if you have a cardiovascular condition — or are likely to develop one — and can't reach your LDL goals with a statin alone, it's a reasonable choice. You know how you feel the best and they want to know about any symptoms so they may give you the best possible treatment. The design of the trial was a 2 X Zetla factorial which consisted of a 2- to week pre-treatment washout phase, a 4-week lead-in placebo Zetis, and a week treatment phase. Due to insufficient data, the manufacturer does not recommend ezetimibe for patients with moderate to severe Zrtia impairment Child-Pugh score 7— Certainly the more choices doctors and patients have, the better. Noting that in9 million Americans were taking Zetia versus just 2. Stabi Pharm. Overall, when ezetimibe was added to simvastatin, there was an additional What is ezetimibe? Therefore, ezetimibe should not be used in nursing mothers unless the benefit clearly outweighs the risk. Combining statins with other available lipid-lowering drugs e. It seems as if they keep moving the "bad" LDL cholesterol goal line so it's harder to reach. Published: March, Ezetimibe was also well tolerated. Health News. Retrieved 15 July Q: I was taking 40 mg of Zocor daily. But if you remember just a few hours before Zetua next scheduled dose, take only eZtia dose. Your doctor may monitor you eZtia closely if you take these drugs together. Premature coronary atherosclerosis is a major Zetja of hyperlipidemia. You can browse Drugs A-Z Zetia a specific prescription or over-the-counter drug or look up drugs based on your specific condition. Early Saturday morning, Merck issued a press release confirming completion of the merger, stating, "Merck today confirms and underscores its commitment to marketing and developing cardiovascular medicines for a range of cardiovascular disorders. Ezetimibe's pharmacological effect is complementary to that of the statins 1. It may be used by itself or in conjunction with a statin to reduce cholesterol. Turn on desktop notifications for breaking stories about interest? Important considerations for taking ezetimibe. This process is performed in patients with primary hypercholesterolemia because lifestyle changes, such as diet and exercise, and often pharmacotherapy, will not have much influence on LDL cholesterol reduction. The ezetimibe concentration was increased by about 1. Also, multiple peaks are seen on plasma concentration-time profiles, implying enterohepatic recycling.
Common use

Zetia is an antihyperlipidemic agent which used for treating high blood cholesterol along with a low-fat, low-cholesterol diet. Also it is used to treat high blood sitosterol and campesterol along with diet therapy. Heart disease or heart attacks arent prevented by Zetia as tests show.



Dosage and direction

Take this medication orally with or without food/milk. The recommended Zetia dose is 10 mg once daily. Patients who require a larger reduction in LDL-C (over 55%) may be started at 10-40 mg once daily.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.



Precautions

Do not use it without doctor permission. Be careful if you have specific medical conditions then this medicine should not be taken along with statins. This is especially true if you have liver disease or are pregnant or intend to get pregnant. If you are pregnant this drug should only be taken if it is absolutely necessary. If you drink large quantities of alcohol you should be closely monitored by their doctor while they are taking this medication.



Contraindications

Not allowed in people who are hypersensitivity to any component of this medication. The combination of Zetia with an HMG-CoA reductase inhibitor is not allowed in patients with active liver disease or unexplained persistent elevations in serum transaminases. All HMG-CoA reductase inhibitors are not allowed in pregnant and nursing women. Myopathy and rhabdomyolysis.



Possible side effect

They may include all types of an allergic reactions. Also the most possible side effects include:

unusual muscle weakness, tenderness, or pain;

loss of appetite, nausea, clay-colored stools, stomach pain, low fever, dark urine, jaundice;

chest pain;

pancreatitis;

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Less serious include:

numbness or tingly feeling;

mild stomach pain, diarrhea;

tired feeling;

headache;

dizziness;

depressed mood;

runny or stuffy nose, cold symptoms;

joint pain, back pain; or

cough.

If you experience one of them stop using Zetia and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Zetia interact with the following medications: cholestyramine (Prevalite, Questran); colestipol (Colestid); colesevelam (Welchol); gemfibrozil (Lopid); cyclosporine (Neoral, Sandimmune, Gengraf); or a blood thinner such as warfarin (Coumadin).

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Symptoms of Zetia overdose are not known but it can be harmful.

If you experience one of them call your doctor immediately.



Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Women's Health

Talking about women's health we usually mean a number of issues that are associated with women's physiology and anatomy. These issues usually includes gynecological diseases, pregnancy and breastfeeding, menopause, contraception and diseases that are peculiar only to women sex.

Gynecological diseases usually includes infectious diseases that are transmitted through the sexual intercourse. These may be viral, bacterial or fungal infection. The gynecological infections usually manifest in the form of inflammation, edema, redness, itching, discharges, pain in the pelvic area.

Menstruation, pregnancy and breastfeeding are related to the women's reproductive system. Menstruation is a physiological process manifested in rejection of the functional endomethrium layer and vaginal bleeding. Usually a women have a regular menstrual cycle. The disorders of the menstrual cycle can be caused by the hormonal changes, infectious diseases.

Pregnancy includes such issues as

  • Impregnation
  • Carrying of pregnancy and those changes that take place in the women's organism during the pregnancy
  • Act of delivery

If we talk about women's health in women over 45 years we usually talk about 2 conditions : menopause and osteoporosis. Menopause is a period in the women's health when her menstruation stops. In this period a women's organism begins to produce less sex hormones such as estrogens and progestogens. In this period many women complain on hot flashes, night sweats and others. In the period of menopause women usually relieve hormonal replacement therapy.

Another condition that is closely related to menopause is osteoporosis. Osteoporosis is a disease of the bones that becomes fragile and more susceptible to fractures. The treatment of osteoporosis includes life style changes, proper nutrition and certain medication such as Fosamax and Evista.