Generic Zocor (Simvastatin)
Zocor
Zocor is a cholesterol- lowering medication prescribed to inhibit the production of cholesterol by the liver.
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Product Description

Zocor - understood not

Post-marketing experience is after the drug has been approved by the U. Besides cyclosporine, gemfibrozil, and the other medications mentioned above, the following drugs may interact with Zocor — increasing the likelihood of experiencing side effects. Hepatitis A rarely causes liver damage, liver failure, or death. A: The benefits of generic Zocor simvastatin are the same as those associated with the Zocor medication. The recommended starting dose for teens with familial high cholesterol is 10 mg a day, and only 40mg a day maximum. If you take too much overdose Immediately telephone your doctor or Poisons Information Centre telephone 13 11 26or go to accident and emergency at your nearest hospital, if you think that you or anyone else may have taken too much ZOCOR. Simvastatin is indicated for the treatment of high cholesterol and triglycerides. The usual recommended starting dose is 20 to 40 mg administered once daily in the evening. Zocor is indicated as an adjunctive therapy to diet. Disposal If your doctor tells you to stop taking ZOCOR or the tablets have passed their expiry date, ask your pharmacist what to do with any that are left over. Do not take extra medicine to make up the missed dose. Lowering your cholesterol can help lower the risk of stroke, heart attack, and other heart complications. A lipid-lowering diet should be followed while you are taking Zocor. If the victim has collapsed, had a seizure, has trouble breathing, Zoxor can't be awakened, immediately call emergency services at Myopathy sometimes takes the form of oZcor with or without acute renal failure secondary to myoglobinuria, and rare fatalities have occurred. Therefore, concomitant use of these drugs is contraindicated [see Contraindications 4Warnings and Precautions 5. The results of a subgroup analysis in 74 patients Zofor type lV hyperlipidemia from a patient, double-blind, placebo-controlled, 3-period crossover study are presented in Table 6. National Institutes of Health U. The benefits of generic Zocor, and the brand-name medication, in reducing elevated cholesterol levels in certain populations of patients include decreasing total cholesterol levels, decreasing levels of low-density lipoproteins LDLcommonly referred to as bad cholesterol, decreasing triglyceride levels and increasing the levels of high-density lipoproteins HDLcommonly referred to as good cholesterol. Search Search. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. So, itching may or may not be caused by Zocor, but it has been reported. If the symptoms of muscle pain or weakness are accompanied by tiredness, fever, nausea and vomiting, brown or dark-colored urine or yellowing skin, patients should contact their health care provider. What Is Zocor Simvastatin? There have been rare reports of immune-mediated necrotizing myopathy associated with statin use [see Warnings and Precautions 5. Cancer Treatment Research. They are supplied as follows:. Discuss future pregnancy plans with your patients, and discuss when to stop taking ZOCOR if they are trying to conceive. Ask your doctor or pharmacist for a list of the ingredients. The commonly reported side effects include drowsiness, weakness and flu-like symptoms. Doses greater than 40 mg have not been studied in this population. Read our full disclaimer. This blocking of your blood vessels can lead to coronary heart disease such as heart attack and anginaand stroke. If you use these drugs with simvastatin, your doctor may lower your dosage of simvastatin. Simvastatin has important interactions with grapefruit juice and other drugs, including some that are commonly used for the treatment of cardiovascular disease. Inactive Ingredients. Relative to the fasting state, the plasma profile of inhibitors was not affected when simvastatin was administered immediately before an American Heart Association recommended low-fat meal. Because statins have the potential for serious adverse reactions in nursing infants, women who require treatment with ZOCOR should not breastfeed their infants [see Use in Specific Populations 8. Other risk factors include:. It is also sold in combination with ezetimibe as Vytorin, and niacin as Simcor. Disclaimer: Our goal is to provide you with the most relevant and current information. Retrieved 19 July But with discount cards, formularies, and special offers, it's hard to say how that will correspond to the price you pay. It is particularly important to tell your doctor if you are taking:. Here Are 11 Ways to Cope. Innovation Management - Strategies, Implementation, and Profits. Study Description. I also get dark Zockr under my eyes and that appears better Zocor I don't take the Zocor as opposed to when I do. Zocor is taken by mouth, with or without food once a day, as directed by your healthcare provider. Takemoto M, Liao JK. Is that okay? Digoxin is used to treat heart failure and arrhythmias. Furthermore, no large clinical study has confirmed that coenzyme Q10 can prevent or lessen side effects from statins. Is it the Zocor, or is it just me? What are your concerns? Zocog image. You should always consult your doctor or other healthcare professional before taking Zocor medication. Taking other Zocorr Tell your doctor if you are taking any other medicines, Zoclr medicines that you buy without a prescription from your pharmacy, supermarket or health food shop. In case of overdose, call the poison control helpline at Ezetimibe SCH Some self help measures suggested below may help your condition and help reduce your chances of having CHD. Fluctuations in mood from time to time are normal. Follow all directions given to you by your doctor and pharmacist carefully. Br J Clin Pharmacol. Using simvastatin with colchicine can increase the risk of both myopathy and rhabdomyolysis. Do not take more than 10 mg of simvastatin with diltiazem or verapamil, or more than 20 mg of simvastatin with amlodipine. There are other drugs available to treat your condition. Certain drugs which inhibit this metabolic pathway can raise the plasma levels of simvastatin and may increase the risk of myopathy. Current expert guidelines do not recommend the use of coenzyme Q10 in people taking statins. However, trends in reduced coronary mortality, major coronary events and revascularization procedures were consistent between this group and the total study cohort. Also, small reports suggest that coenzyme Q10 may reduce muscle pain and joint aches associated with the use of statins; however, not all evidence show a benefit. Hebbel RP. The risk of muscle problems is greater for: patients taking higher doses of ZOCOR, particularly the 80 mg dose older patients 65 years of age and older female patients patients with abnormal kidney function patients with thyroid problems. If the symptoms of muscle pain or weakness are accompanied by tiredness, fever, nausea and vomiting, brown or dark-colored urine or yellowing skin, patients should contact their health care provider. Simvastatin is a prescription drug. This is because on rare occasions, muscle problems can be serious, including muscle breakdown resulting in kidney damage that can lead to death. NDC National Drug Code - Each drug product is assigned this unique number which can be found on the drug's outer packaging. If you take this medicine more than once daily, take it with meals. Generic drugs usually cost less than the brand-name version. Browse Drugs and Medicines. Zocor dosage information in more detail. Rhabdomyolysis is rare; hospitalized rhabdomyolysis Zoco in 4. Zoor simvastatin with colchicine can increase the risk Zocor both myopathy and rhabdomyolysis. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Concomitant strong CYP3A4 inhibitors eg, itraconazole, ketoconazole, posaconazole, voriconazole, HIV protease inhibitors, boceprevir, telaprevir, erythromycin, clarithromycin, telithromycin, nefazodonegemfibrozil, cyclosporine, danazol. Recent Public Laws. Instead, the best way to dispose of your medication is through a medicine take-back program. Epub Mar 4. But for most people in the high-risk groups, all the nonmedical steps just won't be enough. Cancer Currents Blog. The risks for myopathy and rhabdomyolysis with simvastatin 80 mg were highest in the first 12 months of treatment, 5 per person-years and 2 per person-years, respectively, and decreased to 1 per person-years and 0. Advise women of childbearing potential to use effective contraception; discontinue if pregnancy occurs. Simvastatin is also used to decrease the amount of fatty substances such as low-density lipoprotein LDL cholesterol ''bad cholesterol'' and triglycerides in the blood and to increase the amount of high-density lipoprotein HDL cholesterol ''good cholesterol'' in the blood. Perspectives series: cell adhesion in vascular biology. The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. A to Z List of Cancer Drugs. Simvastatin is a prescription drug. Drug Class. Patients should also be advised not Zodor eat grapefruit Zocorr drink grapefruit juice while they take Zocor. I thought I was experiencing Zcoor from arthritic knees, then it became apparent it was more muscle and nerve pain. If you experience any of the above symptoms, dark urine or unexplained tiredness you should contact your health care provider. Simvastatin 80 mg-INT, red, oblong, film coated. Kimberly Hotz, PharmD. To check if it has been updated ask your pharmacist. These are serious side effects. Grant Closeout. National Library of Medicine U. Am J Cardiol. Zocor is also used to reduce the risk of heart attack, stroke, and needing certain heart procedures in people at high risk of an adverse heart event. Change in plasma tissue factor TF levels after treatment with simvastatin. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. Nursing mothers. In fact, its wholesale price is often lower. Listing a study does not mean it has been evaluated by the U.
Common use

Zocor is a cholesterol-lowering medication which used to treat high cholesterol levels in the blood. It works by blocking the production of cholesterol in the body, thus can help prevent conditions that can lead to heart attack, heart disease and hardening of the arteries, stroke, and vascular disease. This medication can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke. Use this medication during low fat diet to get the best result.



Dosage and direction

Take this medication orally with or without food/milk.

The recommended starting dose of Zocor for adults is 20 to 40 milligrams once a day in the evening. The dosage can be varied every 4 weeks.

The recommended starting dose for children 10 to 17 years old is 10 milligrams once a day in the evening. The dosage can be varied every 4 weeks, but should not exceed 40 mg a day. Girls must have been menstruate for at least 12 months before starting therapy with Zocor.

Children under 10 years old only after doctor permission.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.



Precautions

Before taking Zocor consult with your doctor if your medical history include: history of alcoholism, liver disease, severe infection, kidney disease, low thyroid function, heart disease, allergies. Try to limit alcohol intake because it can increase side effects. Also note: Zocor may increase your risk for liver problems. During the treatment with Zocor you may to limit the amount of grapefruit or grapefruit juice you may eat or drink (less than 1 quart a day) , because grapefruit juice may increase your risk for serious side effects.

For woman: Zocor should not be used during pregnancy, becoming pregnancy or lactating. Do not use before breast-feeding without doctor's permission.



Contraindications

Zocor is not allowed in patients with active liver disease or unexplained persistent elevations of serum transaminases or who are hypersensitivity to any component of this medication. Pregnancy and lactation. Atherosclerosis is a chronic process and the discontinuation of lipid-lowering medications during pregnancy should have little impact on the outcome of long-term therapy of primary hypercholesterolemia. Ability of inhibitors of HMG-CoA reductase such as Zocor can decrease the synthesis of cholesterol and possibly other products of the cholesterol biosynthesis pathway, so Zocor is contraindicated during pregnancy and in nursing mothers. Zocor should be administered to women of childbearing age only when such women are highly unlikely to become pregnant. If the patient conceve while taking this drug, Zocor should be discontinued immediately and the patient should be apprised of the potential hazard to the fetus



Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.

Less serious include:

mild stomach pain, gas, bloating, stomach upset, heartburn;

nausea;

constipation; or

diarrhea.

If you experience one of them stop using Serevent and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Zocor interact with such types of drugs as: danazol; gemfibrozil (Lopid), clofibrate, or fenofibrate;

niacin; nefazodone; cholestyramine or colestipol; warfarin; amiodarone, diltiazem, or verapamil;

erythromycin, clarithromycin, or telithromycin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as amprenavir, indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Overdose of Zocor is not danger for you life and iclude such symptoms: myalgia and red urine (in a severe overdose). If you experience one of them call your doctor immediately.



Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Women's Health

Talking about women's health we usually mean a number of issues that are associated with women's physiology and anatomy. These issues usually includes gynecological diseases, pregnancy and breastfeeding, menopause, contraception and diseases that are peculiar only to women sex.

Gynecological diseases usually includes infectious diseases that are transmitted through the sexual intercourse. These may be viral, bacterial or fungal infection. The gynecological infections usually manifest in the form of inflammation, edema, redness, itching, discharges, pain in the pelvic area.

Menstruation, pregnancy and breastfeeding are related to the women's reproductive system. Menstruation is a physiological process manifested in rejection of the functional endomethrium layer and vaginal bleeding. Usually a women have a regular menstrual cycle. The disorders of the menstrual cycle can be caused by the hormonal changes, infectious diseases.

Pregnancy includes such issues as

  • Impregnation
  • Carrying of pregnancy and those changes that take place in the women's organism during the pregnancy
  • Act of delivery

If we talk about women's health in women over 45 years we usually talk about 2 conditions : menopause and osteoporosis. Menopause is a period in the women's health when her menstruation stops. In this period a women's organism begins to produce less sex hormones such as estrogens and progestogens. In this period many women complain on hot flashes, night sweats and others. In the period of menopause women usually relieve hormonal replacement therapy.

Another condition that is closely related to menopause is osteoporosis. Osteoporosis is a disease of the bones that becomes fragile and more susceptible to fractures. The treatment of osteoporosis includes life style changes, proper nutrition and certain medication such as Fosamax and Evista.